propranolol in infantile hemangioma: a review article
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abstract
hemangioma is the most common benign cutaneous vascular tumor in infants and children. the hemangioma incidence in the neonates is 2% to 3% that increases to 10% in those younger than one year of age. before introduction of propranolol in 2008, different medications such as systemic corticosteroids and vincristine, with different side effects, were used for years. since then, over 200 studies concerning propranolol administration have been published. this study reviews propranolol use in infantile hemangioma.
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Infantile hemangioma is a common tumor of infancy. Although most hemangiomas spontaneously regress, treatment is indicated based on complications, risk to organ development and function, and disfigurement. The serendipitous discovery of propranolol, a non-selective β-adrenergic receptor blocker, as an effective means to regress hemangiomas has made this a first-line therapy for hemangioma patie...
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Infantile hemangiomas are proliferative vascular disorders that occur in the pediatric airway, potentially causing airway narrowing and respiratory stress. It appears in 1 out 10 children, more frequently in girls. Hemangiomas are benign tumours that usually appear on the head or neck but may also occur in deep organs. Until recently, the most common medical therapy used was high-dose systemic ...
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Infantile hemangiomas as frequent infancy tumors have been a controversial issue of medical scientists worldwide. Their clinical aspects are various and their physiopathology is yet to be fully understood. Numerous publications outline the characteristics, causes, evolution possibilities and therapeutic approaches. Deciding whether to treat or not is the main question of this kind of pathology....
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Journal title:
journal of skin and stem cellجلد ۱، شماره ۲، صفحات ۰-۰
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